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LSASS.EXE - System Error, security accounts manager initialization failed because of the following error: Directory Services cannot start. Error status 0xc00002e1.
I know everyone's scenario's when seeing this message are pretty varied but I found a nice way to fix this within an hour providing you have a similar setup.
In my particular case I had two servers an SBS 2000 (oh dear I hear you cry) and a Standard Server 2003 running SP1. The 2K3 machine was rebooted and upon reboot we were presented with the above error.
So to fix try the following:
1. Reboot the 2K3 server into "Directory Services Restore Mode" then logon to the machine locally, in my case I didnt know the restore password (results of taking on machines from other support companies.)
-If this is the case go onto the second server, right click "my computer" and select manage, within the new window, right click the "Computer Management" header and then click connect to another compu…
I found quite a neat little trick, whether or not the following technical processes are by design I dont know but I assure you this has worked for me loads of times.
If you see Sophos Anti Virus with a red shield in it, first thing I used to do is rename the Cache folder in Program Files and then click update. Job done, it updates we can all go home with a smile on our faces.
What I noticed recently was that this didnt fix the problem at all, it generally made a bit more of a mess.
So, if you find that the Cache folder has an update in there (Usually 68Mb+) Navigate to: C:\Program Files\Sophos\AutoUpdate\cache\savxp and click Install Sophos Anti Virus, this will run you through a quick WinInstaller and then update the program.
You will probably have to reboot at this point, you can choose to reboot, usually I just log off ;) (As im sure most IT pro's do)
Finally just re-enter the update credentials into the Sophos program and re-check for updates.